Regioselectivity of ring-opening reactions of optically active N-acetyl-2-methoxycarbonylaziridine

Autor:	Fabio Prati, Irene Moretti, Giovanni Torre, Arrigo Forni, Maria Bucciarelli
Rok vydání:	1995
Předmět:	Inorganic Chemistry Nucleophile Chemistry Organic Chemistry Regioselectivity Organic chemistry Physical and Theoretical Chemistry Optically active Ring (chemistry) Brønsted–Lowry acid–base theory Medicinal chemistry Catalysis Lewis acid catalysis
Zdroj:	Tetrahedron: Asymmetry. 6:2073-2080
ISSN:	0957-4166
DOI:	10.1016/0957-4166(95)00270-y
Popis:	(S)-(−)-N-acetyl-2-methoxycarbonylaziridine 1 undergoes easy ring-opening by Bronsted acids or nucleophiles in the presence of a Lewis acid catalyst. The regioselectivity is not always exclusive, affording optically active α- and β-aminoacids.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::bddd7dbea6f0e338bdc4d1db475119be https://doi.org/10.1016/0957-4166(95)00270-y Zobrazit plný text záznamu Full Text from ScienceDirect