A Palladium on Carbon Catalyzed One-Pot Synthesis of Substituted Benzimidazoles

Autor:	Anjan Bhattacharyya, Soumen Joardar, Saktipada Das
Rok vydání:	2014
Předmět:	Reaction conditions chemistry.chemical_compound chemistry Intramolecular force Palladium on carbon Organic Chemistry One-pot synthesis chemistry.chemical_element Nitro reduction Combinatorial chemistry Catalysis Palladium
Zdroj:	Synthesis. 46:3121-3132
ISSN:	1437-210X 0039-7881
DOI:	10.1055/s-0034-1378454
Popis:	A new and efficient palladium on carbon catalyzed one-pot intramolecular nitro reduction/cyclization reaction has been developed for the preparation of a series of substituted benzimidazoles, including some novel ring-fused [1,2-a]-tricyclic, [1,2-a]-tetracyclic, and chiral benzimidazoles. The main advantages of this method are the mild and simple reaction conditions, the easy isolation of the products, and the excellent yields. The reaction has the potential to be used as a general procedure for the preparation of 7-aminobenzimidazoles in good yields. A plausible mechanism for the reaction is proposed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::bdd70d10611023291aad0d8ee399437b https://doi.org/10.1055/s-0034-1378454 Zobrazit plný text záznamu