Reactions of (RP)- and (SP)-tert-butylphenylphosphinobromidates and tert-butylphenylthionophosphinochloridates with heteroatom nucleophiles; preparation of P-chiral binol phosphinates and related compounds

Autor:	Wai-Kuen Chan, Tin-Lok Au-yeung, Lam-Lung Yeung, Richard K. Haynes, Ka-Yee Chan, Ian D. Williams
Rok vydání:	2001
Předmět:	chemistry.chemical_compound Nucleophile chemistry Phosphorus Organic Chemistry Drug Discovery Heteroatom Phenol chemistry.chemical_element Biochemistry Medicinal chemistry Inversion (discrete mathematics)
Zdroj:	Tetrahedron Letters. 42:453-456
ISSN:	0040-4039
DOI:	10.1016/s0040-4039(00)01950-x
Popis:	Reaction of (RP)- and (SP)-tert-butylphenylphosphinobromidates and tert-butylphenylthionophosphinochloridates with metallated phenol and BINOL alkoxides, thioalkoxides, amides and enolates leading with clean inversion at phosphorus to phosphinates, phosphinothiolates and phosphinoamidates, and the corresponding thionophosphorus compounds are described.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::bdcbeb5190b901f0dae6494bce216740 https://doi.org/10.1016/s0040-4039(00)01950-x Zobrazit plný text záznamu Full Text from ScienceDirect