Multimorbidity is a risk factor for obstructive sleep apnea-hypopnea syndrome in ageing

Autor: Christos F. Kleisiaris, Zoe Daniil, George Markakis, Evangelos I. Kritsotakis, Ioanna V. Papathanasiou, Konstantinos I. Gourgoulianis, Foteini Malli
Rok vydání: 2015
Předmět:
Zdroj: 4.2 Sleep and Control of Breathing.
Popis: Background: Obstructive Sleep Apnea-Hypopnea Syndrome (OSAHS) and chronic comorbid diseases are more prevalent in the elderly. However, little is known about the association of OSAHS with the coexistence of multiple chronic diseases in primary care (PC) patients. Aims: To investigate the prevalence of OSAHS and its relation to multimorbidity in an elderly population attending (PC) settings. Methods: A screening program to detect OSAHS was performed in 16 (PC) settings. A high pre-test likelihood for OSAHS was assessed using the Berlin Questionnaire and the Epworth Sleepiness Scale. Multimorbidity was defined as the coexistence of two or more chronic diseases as documented in the medical records of the study subjects. Bivariate associations were described using odds ratios (OR) with 95% confidence intervals (CI). Results: 490 subjects (50.6% males, mean age±SD 77.5±6.9). High risk for OSAHS, excessive daytime sleepiness and multimorbiditywere observed in 33.5%, 11.6% and43.6% of subjects, respectively.Patients with a history of stroke were more likely to present a high risk for OSAHS (OR=2.06; CI:0.90-4.07), history of cardiovascular disease (OR=1.34; CI:0.91-1.38), diabetes mellitus (OR=1.33; CI: 0.87-2.05) and history of mental disorders (OR=1.34; CI:0.77-2.32) compared to patients without a history of chronic diseases. The associations were not statistically significant. However, patients with a history of 3 or more comorbidities were significantly more likely to present a high-risk for OSAHS (OR=3.03;CI: 1.22–3.64). Conclusion: This study suggests that the coexistence of chronic comorbid diseases is associated with a higher risk for OSAHS in elderly primary care patients.
Databáze: OpenAIRE