The Relation of Ribosomal RNA to the Genome11The experiments performed in the authors' laboratory were supported by Public Health Service Research Grant CA-01094 from the National Cancer Institute and a grant from the National Science Foundation

Autor: S. A. Yankofsky, S. Spiegelman
Rok vydání: 1965
Předmět:
DOI: 10.1016/b978-1-4832-2734-4.50048-6
Popis: Publisher Summary This chapter discusses the relation of ribosomal RNA to the genome. The Watson–Crick model implies that each strand of the duplex serves as a template for the formation of a complementary copy in the replication of DNA. This suggested a genetic transcription mechanism involving the synthesis of complementary RNA copies of the DNA. Proof that the translatable RNA message fraction was complementary to homologous RNA was obtained with the DNA viruses by the use of DNA–RNA hybridization. Two alternatives could be entertained for the origin of ribosomal RNA. One would assume generation by a DNA-dependent reaction, and the other would invoke a synthetic mechanism independent of DNA.
Databáze: OpenAIRE