A study of bovine proteoglycan-II as a growth promotant
| Autor: | C Gazzola, DB Lindsay |
|---|---|
| Rok vydání: | 1993 |
| Předmět: |
Proteoglycan II
chemistry.chemical_classification medicine.medical_specialty Live weight Peptide Articular cartilage Biology Occipital condyle carbohydrates (lipids) medicine.anatomical_structure Endocrinology chemistry Biochemistry Internal medicine medicine Composition (visual arts) General Agricultural and Biological Sciences Dose rate Dermatan sulfate proteoglycan |
| Zdroj: | Australian Journal of Agricultural Research. 44:221 |
| ISSN: | 0004-9409 |
| DOI: | 10.1071/ar9930221 |
| Popis: | Proteoglycan-II is a dermatan sulfate proteoglycan which binds peptide growth factors, and through this mechanism it has been shown to alter the growth of mammalian cells in culture. The possibility was tested that injections of proteoglycan-II could alter the growth of live animals. Proteoglycan-II from bovine occipital condyle articular cartilage was prepared, authenticated and injected into male Wistar rats. The injection of 125I-proteoglycan-II showed that it was absorbed and metabolized by the rats. Growth studies showed that treatment with proteoglycan-II at two levels of purity and at two dose rates produced no change (P > 0.05) in live weight gain, body composition or food conversion efficiency. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|