Neue Wege der Strahlentherapie des Bronchialkarzinoms: Die endobronchiale Kleinraumbestrahlung mit der Iridium-192-High-dose-After-loading-Technik in Kombination mit dem Neodym-YAG-Laser
| Autor: | W. Schumacher, M. Stadler, D. Krumhaar, K. Koch, R. Loddenkemper, J. Mai, H. N. Macha |
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| Rok vydání: | 2008 |
| Předmět: |
Bronchus
medicine.medical_specialty medicine.diagnostic_test business.industry medicine.medical_treatment General Medicine Pulmonary function testing Surgery Endoscopy Radiation therapy medicine.anatomical_structure Bronchial carcinoma medicine Arterial blood Irradiation business Nuclear medicine Perfusion |
| Zdroj: | DMW - Deutsche Medizinische Wochenschrift. 111:687-691 |
| ISSN: | 1439-4413 0012-0472 |
| DOI: | 10.1055/s-2008-1068513 |
| Popis: | 106 patients with inoperable malignant tumours constricting the central bronchial tree underwent endobronchial small-field radiotherapy with iridium-192 at high dose between June 1983 and September 1985. Treatment was performed using the computer-guided after-loading technique and a flexible bronchoscope under local anaesthesia. In complete occlusion of a bronchus by the tumour, a neodymium YAG-laser was applied (57 patients) to allow insertion of the after-loading probe. Endoscopy showed tumour regression in 75% of the patients, accompanied by clinical improvement. Pulmonary function tests, arterial blood gas analyses and pulmonary perfusion scans yielded a highly significant improvement of data after treatment. The procedure also proved effective upon exhaustion of external radiation. Apart from its positive palliation, endobronchial small-field radiotherapy using high doses of iridium-192 also has a curative effect, thus opening up a new approach to the therapy of advanced bronchial carcinoma. |
| Databáze: | OpenAIRE |
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