Enterococcus faecium CMUL1216 an Immunobiotic Strain with a Potential Application in Animal Sector
| Autor: | Mazen Zaylaa, Samah Mechmchani, Imad Al Kassaa, Khaled El Omari, Fouad Dabboussi, Monzer Hamze, Mohamad Bachar Ismail |
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| Rok vydání: | 2021 |
| Předmět: |
0106 biological sciences
0303 health sciences biology 030306 microbiology medicine.drug_class Antibiotics Public Health Environmental and Occupational Health Biofilm biology.organism_classification Antimicrobial Antibiotic misuse 01 natural sciences Applied Microbiology and Biotechnology law.invention Microbiology 03 medical and health sciences Probiotic Antibiotic resistance Enterococcus law 010608 biotechnology medicine Enterococcus faecium |
| Zdroj: | Biocontrol Science. 26:75-84 |
| ISSN: | 1884-0205 1342-4815 |
| DOI: | 10.4265/bio.26.75 |
| Popis: | Antibiotic misuse in the animal sector is the first cause of the emergence and spreading of MDR bacteria. Prevention of infectious diseases and enhancement of animal growth are the main effects of antibiotics that push farmers and veterinarians to use this molecule in animal farms. Thus, the use of alternative solutions such as natural antimicrobial substances as well as probiotic strains is a crucial need in this sector. Enterococcus faecium CMUL1216 was isolated from healthy human baby's feces. This strain was assessed in vitro for probiotic properties including activity against many pathogens isolated from animal, human, and soil samples. CMUL1216 strain exhibits good antimicrobial activity against indicator pathogens in both planktonic and biofilm forms. In addition, CMUL1216 strain showed a strong biofilm formation. Furthermore, CMUL1216 exhibits a good anti-inflammatory effect by inducing the secretion of IL-10 in vitro. Moreover, this strain did not show any pathogenic characteristics such as hemolytic effect, presence of virulence genes as well as susceptibility to the majority of antibiotic families. E. faecium CMUL1216 could be a good candidate to be used a probiotic strain in the animal sector in order to maintain animal health and therefore reduce antibiotic resistance caused by the excessive use in this sector. |
| Databáze: | OpenAIRE |
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