Synthesis of Novel Mannose-Based Crown Ethers

Autor:	Andreas Rathjens, Joachim Thiem
Rok vydání:	2005
Předmět:	Ring size chemistry.chemical_classification chemistry.chemical_compound chemistry Dibutylstannane Stereochemistry Disaccharide Mannose General Medicine Carbohydrate Ring (chemistry) Crown ether Catalysis
Zdroj:	ChemInform. 36
ISSN:	1522-2667 0931-7597
DOI:	10.1002/chin.200522197
Popis:	A novel class of chiral crown ether analogues incorporating carbohydrate subunits can be easily prepared from methyl a-D-mannopyranoside. By a short reaction sequence involving either alkylations using a dibutylstannane intermediate or by phase transfer catalyzed etherification well defined disaccharide mimetics were obtained, which are suitable starting materials in Richman-Atkins cyclizations. The combination of several various reaction partners led to structurally interesting ring systems differing in ring size, number of carbon and hetero atoms (20-40) as well as kind of sugar subunits.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::bd8c30c5dcd95cd3d52df52a83fb5b1e https://doi.org/10.1002/chin.200522197 Zobrazit plný text záznamu Plný text