Method Development for Quantitative Determination of Ascorbic Acid by High-Performance Thin-Layer Chromatography
Autor: | A. I. Slivkin, E. F. Safonova, O. V. Trineeva |
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Rok vydání: | 2018 |
Předmět: |
Pharmacology
Chromatography Chemistry media_common.quotation_subject 010401 analytical chemistry Thin layer Pharmacology toxicology 02 engineering and technology Raw material Ascorbic acid 01 natural sciences Cosmetics Method development Quantitative determination 0104 chemical sciences 020401 chemical engineering Drug Discovery High performance thin layer chromatography 0204 chemical engineering media_common |
Zdroj: | Pharmaceutical Chemistry Journal. 51:938-944 |
ISSN: | 1573-9031 0091-150X |
Popis: | An economic and rapid procedure for identification and quantitative determination of ascorbic acid using high-performance thin-layer chromatography (HPTLC) was developed. The optimum conditions for chromatography of vitamin C on a thin layer of absorbent with quantitative interpretation of the HPTLC data were established experimentally and justified theoretically. The proposed procedure was validated using medicinal plant raw materials such as nettle leaves and sea-buckthorn fruit. The procedure could be used for quality control of substances, single-component and complex preparations, plant materials, biologically active supplements, premixes, and products of the food and cosmetics industries. |
Databáze: | OpenAIRE |
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