| Autor: |
Roland Frankenberger, Nicole B Arweiler, Timo A Sorsa, Gerd Volland, Georg Gaßmann, Cornelia Fietz, Helena Thiem, Reinhard P T Rychlik |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Journal of Pharmaceutical Health Services Research. 13:52-60 |
| ISSN: |
1759-8893 |
| DOI: |
10.1093/jphsr/rmac008 |
| Popis: |
Objectives Active matrix metalloproteinase-8 (aMMP-8) biomarkers can be used in chair side tests for the detection of periodontitis or peri-implantitis and for targeting and monitoring individual therapy. Combined with effective secondary preventive measures, this procedure can reduce tooth loss and related costs. The authors evaluated whether out-of-pocket costs for the patient can be saved additionally. Methods A health economic evaluation of the total costs for secondary preventive versus prosthodontic measures was performed from the patient’s perspective using a Markov-based state transition model with three health states of periodontitis. The intervention group used aMMP-8 biomarker diagnostics in addition to standard prevention services in Germany; the control group received standard care only. Starting age of the patients was 35 years; the modelled period was 50 years. Additionally, a first estimate of the costs for patients with implants for a period of three decades was made. Key findings In the first decade (age group 35–44 years), patients from the intervention group initially have to bear additional costs of 929.53 € compared with the control group. From the age group 45–54 years, the savings potential for the patient increases continuously. Total costs of the intervention group, including additional aMMP-8 assessments, are 32 310.82 € compared with 47 452.04 € in the control group for the 50-year period. The greatest savings potential for patients with aMMP-8 screening and monitoring is in the field of dentures (−18.521.91 €). For the subgroup of patients with implants, the first cost statement leads to costs of 12 672.66 € with additional use of aMMP-8 biomarker diagnostics (control group: 23 185.83 €). Conclusions Despite higher initial costs, secondary prevention not only improves oral health but also importantly can save significant costs in the long run. Especially in implant patients, need-based prevention can prolong the lifetime of dental implants and thus significantly save long-term treatment costs. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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