Analgesic efficacy of sustained release paracetamol in patients with osteoarthritis of the knee
| Autor: | I. Burnett, M. North, T. H. Bacon, J. G. Hole |
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| Rok vydání: | 2002 |
| Předmět: |
Pharmacology
business.industry digestive oral and skin physiology Analgesic Osteoarthritis medicine.disease Acetaminophen law.invention Clinical trial Knee pain Randomized controlled trial Oral administration law Anesthesia Arthropathy medicine Pharmacology (medical) medicine.symptom business medicine.drug |
| Zdroj: | British Journal of Clinical Pharmacology. 53:629-636 |
| ISSN: | 0306-5251 |
| Popis: | Aims Paracetamol is widely recommended as the initial treatment for pain associated with osteoarthritis (OA). A sustained release (SR) paracetamol formulation (Panadol Extend™) was compared with standard immediate release (IR) paracetamol (Panadol™) in patients with knee pain secondary to OA. The primary parameter for assessment of efficacy was patient-assessed global pain relief as determined on day 8 of the treatment period. |
| Databáze: | OpenAIRE |
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