Heterocyclische Verbindungen aus Zuckern, XV: Zur Konfiguration chiraler C-2-substituierter 4-Thiazolidincarbons�uren. Chiralit�tstransfer auf C-3 in 3,4-Dihydro-1H-pyrrolo[1,2-c]thiazolen

Autor:	G. Argay, L. Szilágyi, Alajos Kálmán, Judit Kajtár, Zoltán Györgydeák
Rok vydání:	1994
Předmět:	Oxazolone Munchnones chemistry.chemical_compound Chemistry Stereochemistry Mesoionic Molecule General Chemistry Ring (chemistry) Chirality (chemistry)
Zdroj:	Monatshefte f�r Chemie Chemical Monthly. 125:189-208
ISSN:	1434-4475 0026-9247
Popis:	5-Substituted 3,4-dihydro-pyrrolo[1,2-c]thiazole-6,7-dicarboxylic acid esters3 are obtained from 2-substituted-3-acyl-1,3-thiazolidine-4-carboxylic acids,1 in [3+2]-cycloaddition reactions via mesoionic oxazolone (“munchnone”) intermediates. The chirality at C-4 of the starting carboxylic acids1 is eliminated in the products3, and the chirality at C-3 (C-2 in the starting carboxylic acids1) can thus be determined through chiroptical measurements. Several representatives of the ring system3 have been characterised through1H- and CD-spectra and the molecular structure of (3S)-3da has been determined by X-ray crystallography.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::bd60911ecba580e7250e95a2490bfe9f https://doi.org/10.1007/bf00818164 Zobrazit plný text záznamu Full text from SpringerLink