Does symbiotic supplementation which containsBacillus Coagulans Lactobacillus rhamnosus, Lactobacillus acidophilusand fructooligosaccharide has favourite effects in patients with type-2 diabetes? A randomised, double-blind, placebo-controlled trial
| Autor: | Iman Kareem, Ehsan Hejazi, Meghdad Sedaghat, Omid Nikpayam, Mehdi Hedayati, Golbon Sohrab, Khadijeh Abhari, Aynaz Velayati |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
biology Physiology business.industry Placebo-controlled study 030209 endocrinology & metabolism General Medicine Type 2 diabetes medicine.disease biology.organism_classification Gastroenterology 03 medical and health sciences 0302 clinical medicine Lactobacillus acidophilus Insulin resistance Lactobacillus rhamnosus 030220 oncology & carcinogenesis Physiology (medical) Diabetes mellitus Internal medicine medicine Homeostatic model assessment Bacillus coagulans business |
| Zdroj: | Archives of Physiology and Biochemistry. :1-8 |
| ISSN: | 1744-4160 1381-3455 |
| Popis: | This study aimed to determine the effect of Bacillus Coagulans symbiotic supplementation on metabolic factors and inflammation in patients with type-2 diabetes. In this clinical trial, 50 patients with type-2 diabetes were randomly assigned to the symbiotic (containing Bacillus Coagulans + Lactobacillus rhamnosus + Lactobacillus acidophilus and fructooligosaccharide) or placebo groups to receive one sachet daily for 12 weeks. Glycaemic Index, lipid profile, and hs-CRP were measured at the beginning and end of the study. Analysis of covariance demonstrated that fasting blood glucose (FBG), insulin, homeostatic Model Assessment for Insulin Resistance (HOMA-IR), β-cell function (HOMA-β) (p |
| Databáze: | OpenAIRE |
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