Assessment of Serum Cotinine and Oxidative Stress Markers in Tobacco Users

Autor:	Satish V Kakade, Anuja A. Pawar, Ajit V. Sontakke, Vaishali S. Pawar
Rok vydání:	2019
Předmět:	Pharmacology 030213 general clinical medicine 03 medical and health sciences Serum cotinine 0302 clinical medicine Tobacco users business.industry medicine Physiology medicine.disease_cause business 030217 neurology & neurosurgery Oxidative stress
Zdroj:	Biomedical and Pharmacology Journal. 12:579-586
ISSN:	2456-2610 0974-6242
Popis:	Augmented production of free radicals associated with smoking with decrease in antioxidant levels and increase in peroxidation of biomolecules have been shown in various studies. The studies with smokeless tobacco use having depictive data were lacking. To estimate serum cotinine (CTN) levels and oxidative stress markers in tobacco smokers and smokeless tobacco users and to compare them with tobacco nonusers. This cross sectional study was performed in 180 study subjects divided into 6 groups - tobacco smokers, tobacco chewers, tobacco mishri users, dual tobacco chewers and mishri users, dual smokers and smokeless tobacco users and tobacco nonusers. Serum CTN levels were estimated. Oxidative stress was estimated by Malondialdehyde (MDA) and enzymatic antioxidant Superoxide Dismutase (SOD). Serum MDA levels were significantly high and erythrocytic SOD levels were significantly low in tobacco users than tobacco nonusers (P
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::bd55199a030e567e267733d68df5a376 https://doi.org/10.13005/bpj/1677 Zobrazit plný text záznamu