Latex piezoelectric immunoassay: it's application for clinical and environmental analysis

Autor: Hidenobu Aizawa, N. Minoura, Naoki Kamo, C. Nakamura, Minoru Yoshimoto, M. Muratsugu, Shigeru Kurosawa, Jun Miyake
Rok vydání: 2003
Předmět:
Zdroj: Proceedings of the 1999 Joint Meeting of the European Frequency and Time Forum and the IEEE International Frequency Control Symposium (Cat. No.99CH36313).
DOI: 10.1109/freq.1999.841475
Popis: Latex piezoelectric immunoassay (LPEIA) is a new immunoassay method that requires no immobilization of antigen or antibody on the electrode surface of quartz crystal, in contrast to previous immunoassays in which a piezoelectric crystal is used as a microbalance and immobilization is essential. The frequency change was observed during the aggregation of antibody- or antigen-coated latex particles. This method was used for the detection and is sufficiently sensitive for clinical applications. We made a prototype LPEIA sensor for remote sensing and diagnosis to care for a handicapped person in their home.
Databáze: OpenAIRE