Möglichkeiten der objektiven Messung der optischen Dichte der Makula
| Autor: | Gabrielle E. Lang, Dietrich Schweitzer, J. Dawczynski |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Lutein
genetic structures business.industry Flicker Optical density Macular degeneration medicine.disease eye diseases Zeaxanthin Age-related maculopathy Ophthalmology chemistry.chemical_compound Optics chemistry Macular Pigment medicine sense organs Densitometry business Biomedical engineering Mathematics |
| Zdroj: | Klinische Monatsblätter für Augenheilkunde. 228:57-61 |
| ISSN: | 1439-3999 0023-2165 |
| Popis: | Determination of the optical density of the macular pigment may be used for an assessment of the efficacy of oral lutein supplementation in patients with dry AMD. Beside subjective methods like heterochrome flicker photometry, objective methods like the 2-wavelength auto-fluorescence method and the 1-wavelength reflection method are in clinical use today. Both methods show comparable results. For a long-term assessment of the efficacy of oral lutein supplementation, different parameters like mean and maximal optical density as well as the integral over optical density on all pixels ("volume") should be used. The parameter volume often increases also in cases in which other parameters do not change anymore. The 1-wavelength reflection method is used for the newly initiated LUTEGA study. This study will investigate the long-term effects of a fixed lutein/omega-3-fatty acid combination on the optical density in patients with dry AMD. |
| Databáze: | OpenAIRE |
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