Orofacial clefts and infections during pregnancy
| Autor: | Drahomír Palenčár, Dagmar Fekiačová, Eva Tichá, Molnarova A, Eduard Ujházy, Eva Bieliková |
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| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Congenital cytomegalovirus infection Plant Science 030105 genetics & heredity Biochemistry Rubella Virus 03 medical and health sciences 0302 clinical medicine Genetics medicine 030212 general & internal medicine Statistical processing Molecular Biology Ecology Evolution Behavior and Systematics Pregnancy business.industry virus diseases Cell Biology Hepatitis B medicine.disease Specific antibody Immunology Animal Science and Zoology business Parotitis |
| Zdroj: | Biologia. 73:629-635 |
| ISSN: | 1336-9563 0006-3088 |
| Popis: | Orofacial clefts (OFCs) are common congenital malformations of the lip, palate, or both caused by complex genetic and environmental factors. Specific antibodies against viruses influenza, rubella, cytomegalovirus, Epstein-Barr, parotitis and hepatitis B were investigated serologically in children with orofacial clefts and in their mothers. The results were compared with those obtained in control children and their mothers. Evaluation of the results and their statistical processing supports the assumption that infection during pregnancy may have occurred in the series studied induced by viruses of influenza, rubella, cytomegalovirus and possibly also by the Epstein-Barr virus. No association with the viruses of hepatitis B and parotitis was established. |
| Databáze: | OpenAIRE |
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