The 4-Aminomethylphenoxy-Benzoxaborole AN3057 as a Potential Treatment Option for Primary Amoebic Meningoencephalitis
| Autor: | Kateřina Ženíšková, Jan Mach, Dominik Arbon, Jan Štursa, Lukáš Werner, Martin Zoltner, Robert Sutak |
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| Rok vydání: | 2023 |
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| Zdroj: | Antimicrobial Agents and Chemotherapy. 67 |
| ISSN: | 1098-6596 0066-4804 |
| Popis: | Primary amoebic meningoencephalitis is a rare but fatal central nervous system (CNS) disease caused by the “brain-eating amoeba” Naegleria fowleri . A major obstacle is the requirement for drugs with the ability to cross the blood-brain barrier, which are used in extremely high doses, cause severe side effects, and are usually ineffective. |
| Databáze: | OpenAIRE |
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