Association of Increased Arterial Stiffness with Severity of Coronary Artery Disease in Patients With Non-ST- Segment Elevation Myocardial Infarction

Autor:	Muhammed Aminur Razzaque, Pinaki Ranjan Das, Mohammad Anowar Hossain, Shahana Zaman, Kazi Ashraful Alam, Abdul Kader Akanda, Ashiqur Rahman Khan, Zahidul Islam, Abm Nizam Uddin, Abdullah Al Shafi Majumder
Rok vydání:	2019
Předmět:	medicine.medical_specialty business.industry Elevation General Medicine medicine.disease Coronary artery disease Internal medicine Cardiology Arterial stiffness Medicine ST segment In patient Myocardial infarction business
Zdroj:	Bangladesh Heart Journal. 34:73-79
ISSN:	2521-3113 1024-8714
Popis:	Objective: Cardiovascular diseases (CVDs) have become the single largest cause of death worldwide. The scenario is same in Bangladesh. Increased arterial stiffness has been associated with increased risk of CVD. A noninvasive assessment of arterial stiffness may serve as a useful adjunct to the cardiovascular risk stratification and risk management and it would be of value for the examination of larger populations. So, this study was designed to demonstrate the association between CVD and arterial stiffness. Methods: This cross sectional study was conducted in the National Institute of Cardiovascular Disease, Dhaka over a period of ten months starting from January 2014. Patients were purposively selected from those who were admitted in NICVD with acute Non-ST- Segment Elevation Myocardial Infarction (NSTEMI). A total of 80 patients were included in the study. Study patients were divided into two groups on the basis of aortic augmentation pressure (AP), augmentation index (Aix) and augmentation index corrected at heart rate 75/min (AIx@75). Assessment of coronary angiography was performed and severity was assessed by several scoring systems. Results: Significant positive correlation was found between AIx@75 and vessel score (r= 0.70, p=0.001), Friesinger score (r=0.66, p=0.001) and Leaman score (r= 0.69, p=0.001). Logistic regression analysis showed that increased AIx@75 is significantly associated with severe Coronary Artery Disease (CAD) (OR being 5.54). Conclusion: The results indicate that AP, AIx and AIx@75 are predictors of severity of CAD. It may be considered as a recommended test for the evaluation of cardiovascular risk. Bangladesh Heart Journal 2019; 34(2) : 73-79
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::bd061b2682c84ae674df509cb5e94781 https://doi.org/10.3329/bhj.v34i2.44436 Zobrazit plný text záznamu