Long-term prognosis and predictors of outcomes after childhood convulsive status epilepticus
| Autor: | Suresh Pujar, Snehal Surana |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Pediatrics medicine.medical_specialty Adverse outcomes Convulsive status epilepticus business.industry Incidence (epidemiology) Cognition Status epilepticus medicine.disease 03 medical and health sciences Epilepsy 030104 developmental biology 0302 clinical medicine parasitic diseases medicine Etiology General Earth and Planetary Sciences medicine.symptom business 030217 neurology & neurosurgery General Environmental Science Prolonged seizures |
| Zdroj: | Karnataka Pediatric Journal. 36:13-18 |
| ISSN: | 0975-5152 |
| Popis: | Objective:Childhood convulsive status epilepticus (CSE) is widely known to be associated with short-term and long-term mortality and morbidity, but the role of CSE itself on adverse outcomes is debatable. The additional effect of CSE characteristics on outcomes after CSE and whether prolonged seizures cause any long-term hippocampal injury which leads to developmental or memory impairment is uncertain. This review provides an overview of long-term prognosis after childhood CSE, highlighting data from recent literature.Findings:In previously normal children, the long-term prognosis after childhood CSE is favorable, with low incidence of epilepsy, motor, and cognitive difficulties. Mesial temporal sclerosis is uncommon in children after prolonged febrile seizures. In children with symptomatic causes and those with pre-existing neurological abnormalities, there is substantial morbidity after childhood CSE. Etiology is the primary determinant of outcome after childhood CSE and the additional effect of CSE characteristics such as seizure duration seems to be less than previously believed. |
| Databáze: | OpenAIRE |
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