| Popis: |
ObjectivesThe purpose of the study was to investigate the association between fertility history and cognition function, depression and chronic comorbidity in west China.MethodsWe included 4,276 women aged 50 or older in our study, and we analyzed associations between parity history and cognitive decline, depression, chronic disease comorbidity in west China using univariate and multivariate models. Multivariate models were adjusted for age, ethnic groups, occupation, marriage status, educational level, life style factors, sleeping time and so on. ResultsOf 4,276 women in west China, 18.4% were either childless or had one child, 33.8% had two children, 23.7% had three children, and 24.1% had four or more children. Compared to low parity (0-1 children), having 4 or more children was significantly associated with depression (OR 1.379, 95%CI 1.046-1.819), chronic disease comorbidity (OR 1.714, 95%CI 1.252-2.346), mild cognitive decline (OR 2.179, 95%CI 1.503-3.159) and moderate/severe cognitive decline (OR 1.806, 95% CI 1.064-3.067). Conclusions This study indicated that high parity was significantly associated with poorer cognitive functioning, depression and chronic disease comorbidity. For a better mid-late life health, reproductive women should plan their number of desired children. |
