N-Terminal Kinesins: Many and Various

Autor: Roy Milner, Viki Allan, Marcin J. Wozniak
Rok vydání: 2004
Předmět:
Zdroj: Traffic. 5:400-410
ISSN: 1398-9219
DOI: 10.1111/j.1600-0854.2004.00191.x
Popis: Molecular motors are a fascinating group of proteins that have vital roles in a huge variety of cellular processes. They all share the ability to produce force through the hydrolysis of adenosine triphosphate, and fall into classes groups: the kinesins, myosins and the dyneins. The kinesin superfamily itself can be split into three major groups depending on the position of the motor domain, which is localized N-terminally, C-terminally, or internally. This review focuses on the N-terminal kinesins, providing a brief overview of their roles within the cell, and illustrating recent key developments in our understanding of how these proteins function.
Databáze: OpenAIRE