Finding a single-molecule receptor for citramalic acid through supramolecular chelation

Autor:	Christer B. Aakeröy, John Desper, Michelle M. Smith
Rok vydání:	2015
Předmět:	Molecular recognition Hydrogen bond Stereochemistry Chemistry Organic Chemistry Supramolecular chemistry Molecule Chelation General Chemistry Host–guest chemistry Acceptor Cocrystal Catalysis
Zdroj:	Canadian Journal of Chemistry. 93:822-825
ISSN:	1480-3291 0008-4042
DOI:	10.1139/cjc-2014-0570
Popis:	We have demonstrated that the tritopic hydrogen-bond acceptor 1,3,5-(5,6-dimethylbenzimidazol-1-yl)-2,4,6-trimethylbenzene can act as a perfectly complementary receptor for citramalic acid. The solid-state structure of the cocrystal of the two components show that they form 1:1 pairs where each pair is held together by three near-linear O–H···N hydrogen bonds in a converging manner. The conformational flexibility of both species is apparently no hindrance to the formation of discrete dimeric “cups” wherein each species presents three hydrogen-bond donors/acceptors in a face-to-face orientation.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::bcdf5d54ed86857270eb7e1a849f1ad8 https://doi.org/10.1139/cjc-2014-0570 Zobrazit plný text záznamu Plný text ve formátu PDF