The Regioselective 4-Benzylation of 2,4-Dihydroxybenzaldehyde

Autor:	Jack Dougherty, Wilford Mendelson, Monica M. Holmes
Rok vydání:	1996
Předmět:	Group (periodic table) Chemistry Organic Chemistry Organic chemistry Regioselectivity
Zdroj:	Synthetic Communications. 26:593-601
ISSN:	1532-2432 0039-7911
DOI:	10.1080/00397919608003653
Popis:	A regioselective mono-benzylation of the 4-hydroxyl group of 2,4-dihydroxybenzaldehyde (2) to produce 1 under extremely mild basic conditions (NaHCO3 or KF) has been developed. This approach gives improved regioselectivity relative to earlier methods.
Databáze:	OpenAIRE
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