ChemInform Abstract: Ligand Exchange Reaction of Sulfoxides in Organic Synthesis: A New Method for One-Carbon Homologation of Esters to Carboxylic Acids and Esters via α-Chloro α-Sulfinyl Ketones

Autor:	Y. Mizu, Tsuyoshi Satoh, Yasumasa Hayashi, Koji Yamakawa
Rok vydání:	2010
Předmět:	chemistry.chemical_compound chemistry Ligand chemistry.chemical_element Organic synthesis General Medicine Phenyl sulfoxide Carbon Medicinal chemistry Carbanion
Zdroj:	ChemInform. 25
ISSN:	0931-7597
DOI:	10.1002/chin.199417119
Popis:	Reaction of the Carbanion of chloromethyl phenyl sulfoxide with esters gave α-chloro α-sulfinyl ketones, which were treated with KH followed by t-BuLi to afford one-carbon homologated acids and esters in good to excellent yields.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::bcc63299c82d831b3ff390bc5b4598fc https://doi.org/10.1002/chin.199417119 Zobrazit plný text záznamu Plný text