International Cooperative Ataxia Rating Scale for pharmacological assessment of the cerebellar syndrome
| Autor: | Bala V. Manyam, Paul Trouillas, D. Timann, K. Wessel, Jérôme Honnorat, Robert D. Currier, Alessandro Filla, Alan Bryer, Paula Coutinho, Giuseppe Campanella, Tetsuya Takayanagi, Mark Hallett, Hans-Christoph Diener, S. H. Subramony, Christopher M. Gomez, Norbert Nighoghossian, L. Schut, S. Massaquoi, M. Ben Hamida |
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| Rok vydání: | 1997 |
| Předmět: |
medicine.medical_specialty
Ataxia Neurology Cerebellar ataxia Limb ataxia Neurological disorder medicine.disease Dysarthria Physical medicine and rehabilitation Cerebellar cognitive affective syndrome medicine Physical therapy International Cooperative Ataxia Rating Scale Neurology (clinical) medicine.symptom Psychology |
| Zdroj: | Journal of the Neurological Sciences. 145:205-211 |
| ISSN: | 0022-510X |
| Popis: | Despite the involvement of cerebellar ataxia in a large variety of conditions and its frequent association with other neurological symptoms, the quantification of the specific core of the cerebellar syndrome is possible and useful in Neurology. Recent studies have shown that cerebellar ataxia might be sensitive to various types of pharmacological agents, but the scales used for assessment were all different. With the long-term goal of double-blind controlled trials-multicentric and international-an ad hoc Committee of the World Federation of Neurology has worked to propose a one-hundred-point semi-quantitative International Cooperative Ataxia Rating Scale (ICARS). The scale proposed involves a compartimentalized quantification of postural and stance disorders, limb ataxia, dysarthria and oculomotor disorders, in order that a subscore concerning these symptoms may be separately studied. The weight of each symptomatologic compartment has been carefully designed. The members of the Committee agreed upon precise definitions of the tests, to minimize interobserver variations. The validation of this scale is in progress. |
| Databáze: | OpenAIRE |
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