Pulmonary Vein Isolation for the Treatment of Drug-Refractory Atrial Fibrillation in Adults with Congenital Heart Disease

Autor: Femi Philip, Richard A. Krasuski, Kamran I. Muhammad, Shikar Agarwal, Andrea Natale
Rok vydání: 2012
Předmět:
Zdroj: Congenital Heart Disease. 7:392-399
ISSN: 1747-079X
Popis: Background. Atrial fibrillation (AF) is a common arrhythmia in adults with congenital heart disease (CHD). Long-term antiarrhythmic therapy (AAT) in these patients has significant shortcomings. The safety and efficacy of pulmonary vein antrum isolation (PVAI) for the treatment of AF in CHD is presently unknown. Hypothesis. We hypothesized that PVAI for AF in patients with CHD is effective and safe. Methods. We reviewed a prospective cohort of 4315 patients (age 18) undergoing PVAI for drug refractory AF at a single institution and identified 36 consecutive patients with CHD (single ventricle physiology, tetralogy of Fallot, coarctation of the aorta, ventricular septal defects, atrial septal defects (ASD) and cardiomyopathy resulting from anomalous origin of the left main coronary from the pulmonary artery). A second cohort of 355 consecutive patients with noncongenital structural heart disease (NSHD) (coronary artery disease, valvular heart disease, ejection fraction
Databáze: OpenAIRE