JAUNDICE FROM BISMUTH COMPOUNDS USED IN THE THERAPY OF SYPHILIS

Autor: Ruben Nomland, Edward A. Skolnik, Lawrence L. McLELLAN
Rok vydání: 1938
Předmět:
Zdroj: Journal of the American Medical Association. 111:19
ISSN: 0002-9955
DOI: 10.1001/jama.1938.02790270021006
Popis: Jaundice occurring during the treatment of syphilis has been the subject of a great deal of study. When medication has been thought to be the cause of the jaundice, the arsphenamines have been blamed in almost every instance. Relatively few authorities have suggested that bismuth compounds used in the treatment of syphilis could cause jaundice. Padget and Moore 1 in their two recent reviews of syphilis did not mention bismuth jaundice. Stokes 2 in his textbook also omitted mention of bismuth jaundice. There are a few reports of jaundice occurring after treatment with bismuth compounds, but none go into any detail. In Ruge's 3 review of more than 700 cases of jaundice in patients under treatment for syphilis he mentioned ten who acquired jaundice and had had only bismuth therapy. Langeron 4 observed two cases of bismuth jaundice and cited fifteen reports of the condition made to him personally. He
Databáze: OpenAIRE