Popis: |
Lipids constitute the majority of the brain’s dry mass, yet little is known about their influences on neural stem cell (NSC) biology during development, adulthood, and disease. This review focuses on “neutral” or simple lipids, most prominently fatty acids, and examines the emerging concept that neutral lipid metabolism plays a prominent role in regulating NSC behaviour under physiological and pathological conditions. We also outline technical approaches for advancing the study of lipid metabolism in the brain. |