Fate Through Fat: Neutral Lipids as Regulators of Neural Stem Cells

Autor: Laura K. Hamilton, Karl J.L. Fernandes
Rok vydání: 2017
Předmět:
Zdroj: Stem Cell Biology and Regenerative Medicine ISBN: 9783319493428
Popis: Lipids constitute the majority of the brain’s dry mass, yet little is known about their influences on neural stem cell (NSC) biology during development, adulthood, and disease. This review focuses on “neutral” or simple lipids, most prominently fatty acids, and examines the emerging concept that neutral lipid metabolism plays a prominent role in regulating NSC behaviour under physiological and pathological conditions. We also outline technical approaches for advancing the study of lipid metabolism in the brain.
Databáze: OpenAIRE