Microencapsulation of Anticancer Drugs and Their Dissolution Rate

Autor:	Ryosuke Nemoto, Machiko Echigo, Hisashi Mori, Hideyuki Murota, Akio Goto, Tetsuro Kato, Katsuo Unno
Rok vydání:	1981
Předmět:	Long lasting Coacervate Chemistry In vivo Mitomycin C medicine Pharmacology Dissolution Carboquone In vitro medicine.drug
Zdroj:	Japanese Journal of Hospital Pharmacy. 6:244-250
ISSN:	2185-9477 0389-9098
Popis:	Three potent anticancer drugs, mitomycin C (MMC), adriamycin (ADR) and carboquone (CQ), were microencapsulated with ethylcellulose in the principles of coacervation with certain modifications and the microcapsules thus prepared were examined with the scanning electron microscope. It was demonstrated in vitro and in vivo experiments that the release of action of microencapsulated MMC was made sustained and long lasting. The in vitro release of ADR and CQ from the microcapsules was also examined.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::bc7ba8e1ab7a7c58640f53cfba1ec417 https://doi.org/10.5649/jjphcs1975.6.244 Zobrazit plný text záznamu