THE DEGRADATION OF l-LYSINE IN GUINEA PIG LIVER HOMOGENATE: FORMATION OF α-AMINOADIPIC ACID

Autor: Clara L. Deasy, Geoffrey Keighley, Arie J. Haagen-Smit, Peter H. Lowy, Henry Borsook
Rok vydání: 1948
Předmět:
Zdroj: Journal of Biological Chemistry. 176:1383-1393
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)57152-0
Popis: A summary of the little that is known of the metabolism of lysine in animals is as follows: it is indispensable in the diet, its α-amino group does not participate in reversible transamination reaction in vivo (2), neither the L nor D form is attacked by the appropriate amino acid oxidase, certain e-nitrogen-substituted derivatives can replace lysine in the diet and their α-amino groups are oxidized by amino acid oxidases (3, 4), no α-nitrogen-substituted derivatives yet prepared can substitute for lysine in the diet (4-6).
Databáze: OpenAIRE