The sulfinyl moiety in Lewis base-promoted allylations

Autor:	Lamin M. Kamara, J. Robin Fulton, Simon C. Morton, Gareth J. Rowlands
Rok vydání:	2009
Předmět:	Organic Chemistry Enantioselective synthesis Sulfoxide Biochemistry Medicinal chemistry Benzaldehyde chemistry.chemical_compound Sulfinamide chemistry Allyltrichlorosilane Reagent Drug Discovery Moiety Organic chemistry Lewis acids and bases
Zdroj:	Tetrahedron. 65:9134-9141
ISSN:	0040-4020
DOI:	10.1016/j.tet.2009.09.042
Popis:	By employing Senanayake's oxathiazolidine-2-oxide reagent, a collection of sulfinamides was prepared and provided the first examples of sulfinamides promoting the allylation of benzaldehyde and N-benzoylhydrazones with allyltrichlorosilane. The optimum sulfinamide-derived Lewis base promoter displays comparable activity to the best sulfinyl-based Lewis bases reported. The use of bis-sulfoxides is also discussed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::bc54caa697d1f8a590a9f7fd68ecfbef https://doi.org/10.1016/j.tet.2009.09.042 Zobrazit plný text záznamu Full Text from ScienceDirect