| Autor: | William J. Lemon, Hee-Yung Yang, Don Stredney, Degen Zhuo, Troy Baer, Russell Sears, Bo Yuan, Joe Spitzner, Jian Ping Wang, Ralf Krahe, Fred A. Wright, Al Stutz, Wei D. Zhao |
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| Rok vydání: | 2001 |
| Předmět: | |
| Zdroj: | Genome Biology. 2:research0025.1 |
| ISSN: | 1465-6906 |
| DOI: | 10.1186/gb-2001-2-7-research0025 |
| Popis: | The recent draft assembly of the human genome provides a unified basis for describing genomic structure and function. The draft is sufficiently accurate to provide useful annotation, enabling direct observations of previously-inferred biological phenomena. We report a functionally annotated human gene index placed directly on the genome. The index is based on the integration of public transcript, protein, and mapping information, supplemented with computational prediction. Such a global approach has been described only for chromosomes 21 and 22, which together account for 2.2% of the genome. We estimate that the genome contains 65,000-75,000 transcriptional units, with exonic sequences comprising 4%. |
| Databáze: | OpenAIRE |
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