A comparison of friction behaviour for ex vivo human, tissue engineered and synthetic skin
Autor: | Matt Carré, Sheila MacNeil, Zeike A. Taylor, Steven Ernest Franklin, Roger Lewis, Luciana Bostan |
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Rok vydání: | 2016 |
Předmět: |
Tissue engineered
Materials science integumentary system Mechanical Engineering 02 engineering and technology Surfaces and Interfaces Tribology 021001 nanoscience & nanotechnology Artificial skin Surfaces Coatings and Films 020303 mechanical engineering & transports medicine.anatomical_structure 0203 mechanical engineering Dermis Mechanics of Materials Test platform medicine Tissue engineered skin Elasticity (economics) 0210 nano-technology Ex vivo Biomedical engineering |
Zdroj: | Tribology International. 103:487-495 |
ISSN: | 0301-679X |
DOI: | 10.1016/j.triboint.2016.07.023 |
Popis: | Skin tribology is complex and in situ behaviour of skin varies considerably between test subjects. The main influencing factor, elasticity, varies due to structural and moisture differences. To find a more reliable test platform, for the first time, synthetic and biological (tissue engineered) substitutes were compared to ex vivo skin, epidermis and dermis. Friction initially increased with rising hydration, before decreasing beyond a threshold for all samples. Friction for Synthetic skin and dermis increased at a similar rate to the other samples, but from a different starting point, and friction dropped at lower hydration. Tissue engineered skin could provide a reliable test platform, but the synthetic skin could only be used if the offset in the data is accounted for. |
Databáze: | OpenAIRE |
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