Liver Damage Severity Evaluated by Liver Function Tests and the Nutritional Status Estimated by Anthropometric Indicators

Autor: Edgar M. Vásquez-Garibay, Rocío Macías-Rosales, Alfredo Larrosa-Haro, Erika F. Hurtado-López
Rok vydání: 2012
Předmět:
Zdroj: Handbook of Anthropometry ISBN: 9781441917874
DOI: 10.1007/978-1-4419-1788-1_135
Popis: Pediatric patients with chronic liver disease (CLD) may present impaired growth and acute malnutrition. In most pediatric series the prevalence of these nutritional-related conditions is high. Secondary malnutrition mechanisms include low caloric intake, malabsorption of lipids and fat soluble vitamins and increased energy expenditure. In children younger than 5 years, the degree of liver damage is closely related to growth impairment and their current nutritional status; both may be predicted by liver function tests such as direct bilirubin, albumin and gamma-glutamyl transpeptidase. Anthropometry has been widely used to evaluate the nutritional status of children with CLD. In infants and toddlers, growth can be properly assessed by measuring head circumference and length; in older children growth may be evaluated by height. When ascitis and/or hepatosplenomegaly are present, weight for height might underestimate the current nutritional status. Arm anthropometrics could become an alternative tool in identifying malnutrition since it estimates muscle mass or fat stores; recent observations of DXA in infants with CLD have shown a good correlation between body compartments and arm anthropometric indicators. In addition to its prognostic value, the crucial reason for anthropometrically evaluating a patient with CLD is to recommend nutritional intervention which will improve growth and current nutritional status or at least avoid its deterioration.
Databáze: OpenAIRE