Quantitative incorporation of steroid samples into potassium bromide for infrared microspectrophotometry
| Autor: | W. B. Mason, M. Sparagana |
|---|---|
| Rok vydání: | 1963 |
| Předmět: |
Pharmacology
Aqueous solution Chromatography Potassium bromide Infrared medicine.medical_treatment Organic Chemistry Clinical Biochemistry Inorganic chemistry Infrared spectroscopy Biochemistry Suspension (chemistry) Steroid chemistry.chemical_compound Endocrinology chemistry Phase (matter) medicine Molecular Biology Dissolution |
| Zdroj: | Steroids. 2:245-252 |
| ISSN: | 0039-128X |
| DOI: | 10.1016/0039-128x(63)90003-5 |
| Popis: | Incorporation of samples into KBr by lyophilization can be extended to include -water insoluble steroids by dissolving them in a suitable organic solvent, dispersing the organic phase in aqueous potassium bromide, and freezing the suspension. The frozen suspension is lyophilized without permitting melting to occur. Data showing substantially quantitative Incorporation of hydrocortisone and hydrocortisone acetate are presented. Good infrared spectra have been obtained starting with as little as 3.3 micrograms of hydrocortisone and 1.0 mg of potassium bromide. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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