THE RELATION BETWEEN THE ANTIGEN VALUE OF HOUSE DUST MITE OF HOUSEHOLDS AND CLINICAL SYMPTOM OF CHILDREN WITH ASTHMA

Autor: Hiromi Imaeda, Tsunesaburo Ando, Isamu Watanabe, Mitsuji Iwasa, Yasushi Kanda, Yasunobu Miura, Kazuo Watanabe, Haruo Goto
Rok vydání: 1997
Předmět:
Zdroj: Nihon Shoni Arerugi Gakkaishi. The Japanese Journal of Pediatric Allergy and Clinical Immunology. 11:256-262
ISSN: 1882-2738
0914-2649
Popis: First objects were households of 12 children with asthma (3-12 years) that Dermatophagoides farinae (Der f) specific IgE value was more than 17.5PRU/ml and 12 normal children. The staffs of health center visited the 24 households once a month during five months and gathered dust by cleaner with Dust Sampler. The Dust Sampler is maked of double filters with 16 mesh (1000μ) and 2000 mesh (74μ) and around shape 5cm in diameter. The antigen value of house dust mite was measured by double antibodies sandwich ELISA method of specific monoclonal antibody Dust Checker, The households of children with asthma were cleaned regularly by determined method. The antigen value of house dust mite of 1g dust in shikifuton and bedroom floor of children with asthma decreased, and clinical symptom tended to remit. Second objects were households of 20 children with asthma (2-11 years) that Der f specific IgE value was more than RAST score 2. Once a month during a year their mothers gathered dust by cleaner with Dust Sampler. The monthly mean antigen value of house dust mite increased in autumn and decreased mostly in February and March. It is thinked that shikifuton make major effect on attack of asthma.
Databáze: OpenAIRE