Age changes in fibronectin levels of the drainage system of the eye
| Autor: | Yu. E. Batmanov, M. V. Brodskaya, G. A. Ermolin, E. E. Efremov |
|---|---|
| Rok vydání: | 1989 |
| Předmět: |
chemistry.chemical_classification
medicine.medical_specialty Intraocular pressure Age changes genetic structures biology Chemistry Type II collagen food and beverages Glaucoma General Medicine Anatomy medicine.disease eye diseases General Biochemistry Genetics and Molecular Biology Fibronectin Endocrinology Interstitial tissue Internal medicine medicine biology.protein Extracellular sense organs Glycoprotein |
| Zdroj: | Bulletin of Experimental Biology and Medicine. 108:1673-1675 |
| ISSN: | 1573-8221 0007-4888 |
| DOI: | 10.1007/bf00839722 |
| Popis: | Fibronectin is an extracellular adhesive glycoprotein which can bind selectively with type II collagen, the main constituent of the interstitial tissue of the trabecular system of the human eye [8], it can increase resistance to the outflow of aqueous humor [4, 5], and can thus raise the intraocular pressure. Fibronectin is found in the drainage system of healthy adults [4]. It is not clear, however, whether the content of this protein changes with age. This is an important concept in connection with the sharp increase observed in the fibronectin content during progression of primary open-angle glaucoma [2]. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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