Convergent dynamics of two cells coupled by a nonlinear gap junction

Autor: Jaroslav Stark, Stephen Baigent, Anne E. Warner
Rok vydání: 2001
Předmět:
Zdroj: Nonlinear Analysis: Theory, Methods & Applications. 47:257-268
ISSN: 0362-546X
DOI: 10.1016/s0362-546x(01)00174-2
Popis: A mathematical model for two xenopus cells linked by a gap junction is analysed. The model takes the form of a 4 dimensional singular perturbation problem. Depending upon the coupling strength of the gap junction and the electrogenic pumping, there is either one stable steady state or two stable and one unstable states. Convergence of the dynamics to a steady state is proved by projecting the system onto a 2 dimensional inertial manifold and applying Dulac's test together with the Poincare-Bendixson theorem.
Databáze: OpenAIRE