New synthetic retinoids obtained by palladium-catalyzed tandem cyclisation-hydride capture process

Autor:	Bruno Charpentier, Lucien Stella, Philippe Diaz, Fabrice Gendre
Rok vydání:	1998
Předmět:	inorganic chemicals Tandem Hydride Bioactive molecules Organic Chemistry Enantioselective synthesis chemistry.chemical_element Nanotechnology Biochemistry Combinatorial chemistry Catalysis Enantiopure drug chemistry Scientific method Drug Discovery Palladium
Zdroj:	Tetrahedron. 54:4579-4590
ISSN:	0040-4020
DOI:	10.1016/s0040-4020(98)00169-0
Popis:	A new series of conformationally restricted retinoids (3-aryl-3-methyl-2,3-dihydro-benzofurans) have been prepared through a palladium-catalyzed tandem cyclisation-hydride capture. The use of enantiopure BINAP-Pd catalyst allowed asymmetric synthesis of bioactive molecules.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::bbad16aadfc4d7885d69c0c0ad169365 https://doi.org/10.1016/s0040-4020(98)00169-0 Zobrazit plný text záznamu Full Text from ScienceDirect