Plateletpheresis in the management of thrombocytosis

Autor:	Anthony P. Tartaglia, William B. Scharfman, Edwin G. Taft, Robert B. Babcock
Rok vydání:	1977
Předmět:	medicine.medical_specialty Thrombocytosis business.industry medicine.medical_treatment Immunology Plateletpheresis Cell Biology Hematology medicine.disease Biochemistry Gastroenterology Surgery Myeloproliferative Disorders Internal medicine medicine Platelet Plasmapheresis business
Zdroj:	Blood. 50:927-933
ISSN:	1528-0020 0006-4971
DOI:	10.1182/blood.v50.5.927.927
Popis:	Acute thrombotic and hemorrhagic manifestations of thrombocytosis associated with myeloproliferative disorders may be life threatening. Conventional therapy with radioisotopes and/or cytotoxic drugs may require weeks for effective control of platelet counts. In five patients, plateletpheresis by discontinuous-flow (Haemonetics) or continuous-flow (Aminco Celltrifuge) centrifugation was used as a means of reducing platelet counts acutely. With each procedure, approximately 2–9 X 10(12) platelets were removed, resulting in decrements in platelet counts and relief of symptoms. Plateletpheresis is a useful and safe acute means of controlling platelet counts in myeloproliferative disorders.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::bb77c56f605d525c775335380a060161 https://doi.org/10.1182/blood.v50.5.927.927 Zobrazit plný text záznamu