| Autor: |
Bohumil Hučín, Alois Zapletal, Milan Šamánek, J. Šulc |
| Rok vydání: |
1992 |
| Předmět: |
|
| Zdroj: |
Quality of Life after Open Heart Surgery ISBN: 9789401051668 |
| DOI: |
10.1007/978-94-011-2640-3_29 |
| Popis: |
There are many reasons for an impairment of lung function in patients with congenital cardiac malformation. Cardiomegaly and distended pulmonary arteries occupy a space at the expense of the developing lung [1]. As early as 1887, von Basch found that pulmonary vascular congestion influences the mechanical properties of the lungs [2]. Decreased dynamic compliance was measured in infants with high pulmonary arterial pressure secondary to an increased left-to-right shunt [3]. A significant reduction of lung complaince was found in patients with atrial septal defect and 2- to 4-fold increase in pulmonary blood flow [4]. In addition, many infants with a high pulmonary blood flow suffer from repeated respiratory infections resulting in a long lasting or permanent damage of the lung tissue in some of them. Changes in the structure of pulmonary arteries in pulmonary hypertension can contribute to an increased lung stiffness [5]. A significant increase of pulmonary diffusing capacity has been explained by an increased size of the capillary bed due to an increased pulmonary blood volume in patients with a left-to-right shunt [6,7]. A rich collateral network in cyanotic heart diseases can contribute to an increased lung stiffness, which was demonstrated in patients with transposition of the great arteries [8]. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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