Perspective of Bronchial Responsiveness According to an Inhaled Anti-inflammatory Treatment in Cough Asthma
| Autor: | Yong Hoon Kim, Seung Hyug Moon, Choon-Sik Park, Shin Young Ki |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
Pulmonary and Respiratory Medicine
Budesonide Nedocromil medicine.medical_specialty business.industry Anti inflammatory treatment Airway inflammation respiratory system medicine.disease respiratory tract diseases Infectious Diseases Bronchial hyperresponsiveness Internal medicine Anesthesia medicine Prospective cohort study business After treatment medicine.drug Asthma |
| Zdroj: | Tuberculosis and Respiratory Diseases. 45:1012 |
| ISSN: | 0378-0066 |
| DOI: | 10.4046/trd.1998.45.5.1012 |
| Popis: | Background : It is known that airway inflammation is present in most patients with asthma, but the relationship between symptoms and the severity and nature of airway inflammation has not been established. Cough variant asthma is defined as an asthma in which the dominant symptom is cough, and the condition can be successfully treated with inhaled steroids. This study was performed to evaluate the time course of bronchial responsiveness according to an inhaled anti-inflammatory therapy and the factors which affect the resolution of bronchial responsiveness, and an efficacy of nedocromil to cough asthma. Method: A prospective study for the investigation of bronchial responsiveness according to an inhaled anti-inflammatory treatment in sixty-one cough asthmatics was performed. Twenty-three entered budesonide (), twenty-two entered nedocromil () and sixteen patients entered combined group. The bronchial hyperresponsiveness (BHR) was estimated by methacholine challenge test using counted breath method. The symptom was estimated by 'symptom score'. Reevaluation of BHR and symptom was performed at 2 month after treatment, and if BHR was not resoluted at this time, regarded as a non-responder, and then follow-up of BHR and symptom was performed at 4- and/or 6 month after treatment. Results: The improvement of BHR and symptom was significant in 2 month (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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