Comparison of Attenuation of Hemodynamic Response to Laryngoscopy with Nalbuphine versus Fentanyl in Patients undergoing Laparoscopic Cholecystectomy

Autor: Kainat ., Mahendar ., Udesh Kumar, Gotam Kumar, Maham Anwar, Mehreen Khan
Rok vydání: 2022
Zdroj: Pakistan Journal of Medical and Health Sciences. 16:330-332
Popis: Aim: To compare the hemodynamic response in laryngoscopy with fentanyl versus nalbuphine in patients undergoing laparoscopic cholecystectomy. Study Design: Randomized controlled trial. Place and Duration of Study: Department of Anesthesiology, Surgical Intensive Care and Pain management, Dow University of Health and Science, Dr. Ruth K.M. PFAU, Civil Hospital Karachi from 17th July 2020 to 16th January 2021. Methodology: Sixty patients between the age of 20-60 years of both genders falling under ASA Class-I and II undergoing laparoscopic cholecystectomy for cholelithiasis which were randomly allocated into two treatment groups. Patients in Group A received fentanyl while Group B was given nalbuphine before endotracheal intubation. Outcome variables were mean heart rate and mean diastolic and systolic blood pressure measured 15 minutes after intubation. Results: The mean age was 41.7±11.9 years. There were 21 (35.0%) male and 39 (65.0%) female patients. Mean body mass index was 25.5±2.6 kg/m2. Thirty five (58.3%) patients belonged to ASA Class-I while 25 (41.7%) patients belonged to ASA class-II. There was no statistically significant difference between fentanyl and nalbuphine in terms of mean heart rate 15 minutes after intubation (87.37±3.30vs. 86.33±4.23 bpm; p-value=0.296). However, the mean diastolic (73.23±3.77 vs 81.40±4.79 mmHg; p
Databáze: OpenAIRE