Synthesis and some reactions of aryl 4,5-dichloroisothiazol-3-yl ketones

Autor:	A. I. Bykhovets, Yu. S. Zubenko, Vladimir I. Potkin, Sergey K. Petkevich
Rok vydání:	2007
Předmět:	chemistry.chemical_classification Ketone Aryl Organic Chemistry Medicinal chemistry Chloride Toluene Acylation chemistry.chemical_compound chemistry medicine Piperidine Benzene Alkyl medicine.drug
Zdroj:	Russian Journal of Organic Chemistry. 43:1532-1536
ISSN:	1608-3393 1070-4280
DOI:	10.1134/s1070428007100211
Popis:	By acylation of benzene, toluene, and p-xylene with 4,5-dichloroisothiazole-3-carbonyl chloride the corresponding aryl 4,5-dichloroisothiazol-3-yl ketones were obtained. By reaction of 4,5-dichloroisothiasol-3-yl 4-methylphenyl ketone with piperidine, alkyl(aryl) thiolates, sodium alcoholates, and 2,4-dinitrophenylhydrazine were synthesized 4-methylphenyl 5-piperidyl-4-chloroisothiazol-3-yl ketone, 5-alkyl(aryl)sulfanyl-4-chloroisothiazol-3-yl 4-methylphenyl ketones, 5-alkoxy-4-chloroisothiazol-3-yl 4-methylphenyl ketones, and 2,4-dinitrophenylhydrazone of the initial ketone respectively.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::bb32f29f3c8ec9de18ccc4b09e71daa0 https://doi.org/10.1134/s1070428007100211 Zobrazit plný text záznamu Plný text ve formátu PDF