Genetic variation of high-altitude Ecuadorian population using autosomal STR markers
| Autor: | César Paz-y-Miño, Ana Karina Zambrano, Carmen Gruezo, Jennyfer M. García-Cárdenas, Andrés López-Cortés, Patricia Guevara-Ramírez, C. Rodríguez-Pollit, M. Vela, A. Gaviria, Verónica Yumiceba, Isaac Armendáriz-Castillo, Santiago Guerrero, Paola E. Leone, Gisella Fiallos, Andy Pérez-Villa |
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| Rok vydání: | 2019 |
| Předmět: |
education.field_of_study
010401 analytical chemistry Population Str markers Effects of high altitude on humans 01 natural sciences 0104 chemical sciences Pathology and Forensic Medicine 03 medical and health sciences 0302 clinical medicine Geography Altitude Genetic distance Genetic variation Genetics 030216 legal & forensic medicine education Demography |
| Zdroj: | Forensic Science International: Genetics Supplement Series. 7:62-64 |
| ISSN: | 1875-1768 |
| Popis: | Fifteen autosomal STRs were analyze in order to elucidate the differences between low and high land Ecuadorian population. Seven Ecuadorian geographic areas (Tisaleo-Mocha, Canar, Quito, Rocafuerte, Santa Rosa, Guayaquil and Lago Agrio) from different altitude were selected for the study. After the analysis, little genetic distances were observed between all cities, the more distant cities (FST = 0.02354) were Rocafuerte at an elevation of 17 m.a.s.l. and Quito at 2850 m.a.s.l. and the similar cities (FST = 0.00033) were Rocafuerte (17 m.a.s.l.) and Santa Rosa (10 m.a.s.l). In conclusion, there is not a great genetic distance in the 15 STRs reported in high and low land Ecuadorian population, therefore previously reported frequencies could been used in identification and paternity cases under analysis. |
| Databáze: | OpenAIRE |
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