Targeted Focal Adhesion Kinase Activation in Cardiomyocytes Protects the Heart From Ischemia/Reperfusion Injury

Autor: Taylor, J. M., Hakim, Z. S., Mack, C. P., Cheng, Z., Rojas, M., DiMichele, L. A.
Jazyk: angličtina
Rok vydání: 2012
DOI: 10.17615/b9zq-qb74
Popis: We previously reported that cardiac-restricted deletion of focal adhesion kinase (FAK) exacerbated myocyte death following ischemia/reperfusion (I/R). Here we interrogated whether targeted elevation of myocardial FAK activity could protect the heart from I/R injury.
Databáze: OpenAIRE