Increased neuronal histamine in thiamine-deficient rats
| Autor: | Pertti Panula, E. R. Korpi, M. Sarviharju, Tuula Karhunen, Leena Tuomisto |
|---|---|
| Rok vydání: | 1992 |
| Předmět: |
Pharmacology
0303 health sciences Allergy medicine.medical_specialty Immunology Pharmacology toxicology Toxicology medicine.disease 3. Good health Neuronal histamine 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Endocrinology chemistry Hypothalamus Internal medicine medicine Pharmacology (medical) Thiamine Histamine H3 receptor 030217 neurology & neurosurgery Thiamine deficiency Histamine 030304 developmental biology |
| Zdroj: | Agents and Actions. 36:C354-C357 |
| ISSN: | 1420-908X 0065-4299 |
| Popis: | Previous studies have indicated that thiamine deficiency is associated with clearly elevated histamine concentrations in the rat hypothalamus, whereas other brain regions contain normal amounts of the amine. The purpose of this study was to find out if the increased hypothalamic histamine concentrations are due to increased numbers of mast cells or changes in neuronal histamine stores. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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