HLA antigens in children with meningoccocal meningitis

Autor:	J Zervas, Helen Valassi-Adam, C Constantopoulos, D Zoumboulakis, N Matsaniotis, F Fessas
Rok vydání:	1980
Předmět:	business.industry Incidence (epidemiology) Arthritis Disease Human leukocyte antigen medicine.disease_cause medicine.disease Antigen Relative risk Pediatrics Perinatology and Child Health Immunology medicine Shigella business Meningitis
Zdroj:	Pediatric Research. 14:1415-1415
ISSN:	1530-0447 0031-3998
Popis:	HLA antigens were studied in 37 children with meningococcal meningitis. B27 antigen was found in 10(27%) of the patients. The incidence is significantly higher in the patients as compared with the incidence in normal controls (x2 14.76 , p < 0.001). Relative risk is 5.39. No statistically significant difference was observed in any other antigen. It is of interest that B27 has been related with other common infections such as those caused by salmonella and shigella, which occasionally have uncommon clinical expressions i.e. arthritis. It is believed that a strong association of the disease with a certain phenotype might prove valuable for clinicians even though evidence for genetic linkage is still lacking.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::baf0e89c9a332dd99400cc419461ed51 https://doi.org/10.1203/00006450-198012000-00043 Zobrazit plný text záznamu